5Z21

The ternary structure of D-lactate dehydrogenase from Fusobacterium nucleatum with NADH and oxamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	D-lactate dehydrogenase	polymer	358	40788.8	4	UniProt (Q8RG11) Pfam (PF00389) Pfam (PF02826)	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
2	E, G, I, K (A, B, C, D)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	4	Chemie (NAI)
3	F, H, J, L (A, B, C, D)	OXAMIC ACID	non-polymer		89.0	4	Chemie (OXM)
4	M, N, O, P (A, B, C, D)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 335 (UniProt: Q8RG11)

PDB	External Database	Details
Met -22	-	expression tag
Asn -21	-	expression tag
His -20	-	expression tag
Lys -19	-	expression tag
Val -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ile -11	-	expression tag
Glu -10	-	expression tag
Gly -9	-	expression tag
Arg -8	-	expression tag
His -7	-	expression tag
Met -6	-	expression tag
Glu -5	-	expression tag
Leu -4	-	expression tag
Gly -3	-	expression tag
Thr -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	163155.3
Non-Polymers*	Number of molecules	8
	Total formula weight	3018.0
All*	Total formula weight	166173.3

*Water molecules are not included.