5YZB
Crystal Structure of Human CRMP-2 with S522D-T509D-T514D-S518D mutations crystallized with GSK3b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydropyrimidinase-related protein 2 | polymer | 525 | 57467.8 | 1 | UniProt (Q16555) Pfam (PF01979) In PDB | Homo sapiens (Human) | DRP-2,Collapsin response mediator protein 2,CRMP-2,N2A3,Unc-33-like phosphoprotein 2,ULIP-2 |
| 2 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1 - 525 (UniProt: Q16555)
| PDB | External Database | Details |
|---|---|---|
| Asp 509 | Thr 509 | engineered mutation |
| Asp 514 | Thr 514 | engineered mutation |
| Asp 518 | Ser 518 | engineered mutation |
| Asp 522 | Ser 522 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57467.8 | |
| All* | Total formula weight | 57467.8 |
