5YX2
Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | DNA (cytosine-5)-methyltransferase 3A | polymer | 285 | 32715.7 | 2 | UniProt (Q9Y6K1) Pfam (PF00145) | Homo sapiens (Human) | Dnmt3a,DNA methyltransferase HsaIIIA,M.HsaIIIA |
| 2 | B, D (B, C) | DNA (cytosine-5)-methyltransferase 3-like | polymer | 208 | 24050.5 | 2 | UniProt (Q9UJW3) | Homo sapiens (Human) | |
| 3 | E, F (E, F) | DNA (25-MER) | polymer | 25 | 7699.0 | 2 | synthetic construct | ||
| 4 | G, H, I, J, L... (A, D, E) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | K, M (A, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 6 | O, P, Q, R, S... (A, B, D, C, E...) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 128930.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1321.4 | |
| All* | Total formula weight | 130251.9 |
