5YX2
Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | DNA (cytosine-5)-methyltransferase 3A | polymer | 285 | 32715.7 | 2 | UniProt (Q9Y6K1) Pfam (PF00145) | Homo sapiens (Human) | Dnmt3a,DNA methyltransferase HsaIIIA,M.HsaIIIA |
| 2 | B, D (B, C) | DNA (cytosine-5)-methyltransferase 3-like | polymer | 208 | 24050.5 | 2 | UniProt (Q9UJW3) | Homo sapiens (Human) | |
| 3 | E, F (E, F) | DNA (25-MER) | polymer | 25 | 7699.0 | 2 | synthetic construct | ||
| 4 | G, H, I, J, L... (A, D, E) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) PubChem (753) | |||
| 5 | K, M (A, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (177678424) PubChem (52224398) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (6419189) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (164157219) PubChem (118374891) PubChem (118560068) PubChem (5284331) PubChem (126969526) PubChem (129105892) PubChem (71170554) PubChem (143518505) PubChem (154578335) PubChem (13231890) PubChem (163054214) PubChem (163335525) | |||
| 6 | O, P, Q, R, S... (A, B, D, C, E...) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 128930.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1321.4 | |
| All* | Total formula weight | 130251.9 |
