5YWU

Crystal structure of TREX1 in complex with a inosine contained dsDNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Three-prime repair exonuclease 1	polymer	259	27987.8	2	UniProt (Q91XB0) In PDB	Mus musculus (Mouse)	3'-5' exonuclease TREX1,DNase III
2	C, D	INOSINE CONTAINED DSDNAS	polymer	23	7042.5	2		Homo sapiens
3	A, B, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Sequence modifications

A, B: 1 - 242 (UniProt: Q91XB0)

PDB	External Database	Details
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	70060.7
Non-Polymers*	Number of molecules	4
	Total formula weight	97.2
All*	Total formula weight	70157.9

*Water molecules are not included.