5YVY

Crystal structure of unlinked full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Genome polyprotein	polymer	52	5816.4	1	UniProt (F8J1V3) Pfam (PF01002)	Dengue virus 4
2	B (B)	Genome polyprotein	polymer	618	69431.1	1	UniProt (F8TEL4) Pfam (PF00949) Pfam (PF07652) Pfam (PF20907)	Dengue virus 4

Sequence modifications

A: 49 - 95 (UniProt: F8J1V3)

PDB	External Database	Details
Val 96	-	expression tag
Lys 97	-	expression tag
Thr 98	-	expression tag
Gln 99	-	expression tag
Arg 100	-	expression tag

B: 1 - 618 (UniProt: F8TEL4)

PDB	External Database	Details
Ser 30	Leu 1504	engineered mutation
Ser 31	Phe 1505	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75247.5
All*	Total formula weight	75247.5

*Water molecules are not included.