5YTB
RanY197A in complex with RanBP1-CRM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding nuclear protein Ran | polymer | 216 | 24364.0 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 2 | B (B) | Ran-specific GTPase-activating protein 1 | polymer | 139 | 16249.6 | 1 | UniProt (P41920) Pfam (PF00638) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Chromosome stability protein 20,Perinuclear array-localized protein,Ran-binding protein 1,RANBP1 |
| 3 | C (C) | Exportin-1,Exportin-1 | polymer | 1017 | 116682.1 | 1 | UniProt (P30822) Pfam (PF03810) Pfam (PF08389) Pfam (PF18777) Pfam (PF18784) Pfam (PF18787) Pfam (PF08767) | Saccharomyces cerevisiae (Baker's yeast) | Chromosome region maintenance protein 1,Karyopherin-124,Chromosome region maintenance protein 1,Karyopherin-124 |
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | G, H, J, K, L... (A, C) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) PubChem (312) | |||
| 8 | I, Q, R (C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 9 | O, P (C) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 10 | S, T, U (A, B, C) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A: 1 - 216 (UniProt: P62826)
C: 1 - 376 (UniProt: P30822)
C: 414 - 1052 (UniProt: P30822)
| PDB | External Database | Details |
|---|---|---|
| Ala 197 | Tyr 197 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 537 | Asp 537 | engineered mutation |
| Cys 539 | Thr 539 | engineered mutation |
| Glu 540 | Val 540 | engineered mutation |
| Gln 541 | Lys 541 | engineered mutation |
| Cys 1022 | Tyr 1022 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 157295.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1252.1 | |
| All* | Total formula weight | 158547.8 |
