5YT2

Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R)-5-[(E)-2-{(1R,3aS,7aR)-1-[(R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl}vinyl]-2-(3-hydroxypropyl)cyclohex-4-ene-1,3-diol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Vitamin D3 receptor	polymer	255	28948.4	1	UniProt (P11473) Pfam (PF00104) In PDB	Homo sapiens (Human)	VDR,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1
2	A	(1R,2S,3R)-5-[(E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methyl-6-oxidanyl-heptan-2-yl]-1,2,3,3a,6,7-hexahydroinden-4-yl]ethenyl]-2-(3-oxidanylpropyl)cyclohex-4-ene-1,3-diol	non-polymer		460.7	1	Chemie (90O)
3		water	water		18.0	151	Chemie (HOH)

Sequence modifications

A: 118 - 164 (UniProt: P11473)
A: 216 - 423 (UniProt: P11473)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28948.4
Non-Polymers*	Number of molecules	1
	Total formula weight	460.7
All*	Total formula weight	29409.1

*Water molecules are not included.