5YIE
Crystal Structure of KNI-10742 bound Plasmepsin II (PMII) from Plasmodium falciparum
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Plasmepsin II | polymer | 327 | 36769.6 | 1 | UniProt (Q8I6V3) Pfam (PF00026) | Plasmodium falciparum (isolate 3D7) (isolate 3D7) | |
| 2 | B, C (A) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 2 | Chemie (CPS) PubChem (457060) PubChem (3659871) PubChem (9895216) PubChem (10371606) PubChem (16396400) PubChem (18397788) PubChem (177530666) PubChem (24883538) PubChem (44120060) PubChem (44450441) PubChem (53229977) PubChem (50987450) PubChem (51028881) PubChem (51028882) PubChem (107670) PubChem (71774074) PubChem (90488808) PubChem (91746229) PubChem (91809267) PubChem (53393728) PubChem (58528211) PubChem (102565428) PubChem (122361936) PubChem (122362044) PubChem (131632459) PubChem (133645855) PubChem (137704711) PubChem (146159681) | |||
| 3 | D (A) | (4R)-3-[(2S,3S)-3-[2-[4-[2-azanylethyl(ethyl)amino]-2,6-dimethyl-phenoxy]ethanoylamino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide | non-polymer | 717.9 | 1 | Chemie (8VF) PubChem (46918760) PubChem (49862506) PubChem (75254150) | |||
| 4 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 5 | F (A) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36769.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1970.7 | |
| All* | Total formula weight | 38740.2 |
