5YHT

Crystal structure of a phosphatase from Mycobacterium tuberculosis in complex with its substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histidinol-phosphatase	polymer	267	28652.2	2	UniProt (P95189) Pfam (PF00459)	Mycobacterium tuberculosis H37Rv	HolPase,Histidinol-phosphate phosphatase
2	C, D, H, I (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E (A)	PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER	non-polymer		221.2	1	Chemie (HSA)
4	F, J, K (A, B)	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
5	G (B)	L-histidinol	non-polymer		142.2	1	Chemie (HSO)
6	L, M (A, B)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 2 - 260 (UniProt: P95189)

PDB	External Database	Details
Met -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57304.3
Non-Polymers*	Number of molecules	9
	Total formula weight	909.9
All*	Total formula weight	58214.2

*Water molecules are not included.