5YFN
Human isocitrate dehydrogenase 1 bound with isocitrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isocitrate dehydrogenase [NADP] cytoplasmic | polymer | 421 | 47604.2 | 2 | UniProt (O75874) Pfam (PF00180) | Homo sapiens (Human) | IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase |
| 2 | C, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, G (A) | ISOCITRIC ACID | non-polymer | 192.1 | 2 | Chemie (ICT) | |||
| 4 | F, H (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 414 (UniProt: O75874)
| PDB | External Database | Details |
|---|---|---|
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95208.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 511.1 | |
| All* | Total formula weight | 95719.5 |
