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5YFM

Human isocitrate dehydrogenase 1 bound with NADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Isocitrate dehydrogenase [NADP] cytoplasmicpolymer41446720.23UniProt (O75874)
Pfam (PF00180)
Homo sapiens (Human)IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase
2D, F, H
(A, B, C)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.43Chemie (NAP)
3E, G, I
(A, B, C)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4J, K, L
(A, B, C)
waterwater18.0460Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight140160.7
Non-Polymers*Number of molecules6
Total formula weight2303.1
All*Total formula weight142463.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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