5Y7K
Crystal structure of human DPP4 in complex with inhibitor1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Dipeptidyl peptidase 4 | polymer | 728 | 84462.6 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) In PDB | Homo sapiens (Human) | ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103 |
2 | A, B, C, D | (R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-one | non-polymer | 401.4 | 4 | Chemie (8VU) | |||
3 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 337850.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1605.7 | |
All* | Total formula weight | 339456.2 |