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5Y7K

Crystal structure of human DPP4 in complex with inhibitor1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DDipeptidyl peptidase 4polymer72884462.64UniProt (P27487)
Pfam (PF00930)
Pfam (PF00326)
In PDB
Homo sapiens (Human)ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103
2A, B, C, D(R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-onenon-polymer401.44Chemie (8VU)
3waterwater18.0272Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight337850.5
Non-Polymers*Number of molecules4
Total formula weight1605.7
All*Total formula weight339456.2
*Water molecules are not included.

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