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5Y7K

Crystal structure of human DPP4 in complex with inhibitor1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Dipeptidyl peptidase 4polymer72884462.64UniProt (P27487)
Pfam (PF00930)
Pfam (PF00326)
Homo sapiens (Human)ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103
2E, F, G, H
(A, B, C, D)
(R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-onenon-polymer401.44Chemie (8VU)
3I, J, K, L
(A, B, C, D)
waterwater18.0272Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight337850.5
Non-Polymers*Number of molecules4
Total formula weight1605.7
All*Total formula weight339456.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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