5Y56
Fc mutant (K392D/K409D/D399K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Immunoglobulin gamma-1 heavy chain | polymer | 208 | 23590.6 | 2 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (Human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | C (C) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 1 | In PDB GlyTouCan (G55659LV) | |||
| 3 | D (D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1276.2 | 1 | In PDB GlyTouCan (G86664UH) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A, B: 236 - 443 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Asp 392 | Lys 394 | engineered mutation |
| Lys 399 | Asp 401 | engineered mutation |
| Asp 409 | Lys 411 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47181.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2901.6 | |
| All* | Total formula weight | 50082.8 |
