5Y4Q
Crystal structure of Trypanosoma cruzi spermidine synthase in complex with N-(4-methoxyphenyl)quinolin-4-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Spermidine synthase, putative | polymer | 304 | 34103.7 | 4 | UniProt (Q4DA73) Pfam (PF17284) Pfam (PF01564) In PDB | Trypanosoma cruzi (strain CL Brener) | |
2 | A, B, C, D | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE | non-polymer | 356.4 | 4 | Chemie (S4M) | |||
3 | A, B, C, D | N-(4-methoxyphenyl)quinolin-4-amine | non-polymer | 250.3 | 4 | Chemie (8OF) | |||
4 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 296 (UniProt: Q4DA73)
PDB | External Database | Details |
---|---|---|
Met -7 | - | expression tag |
Ala -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 136414.9 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2427.0 | |
All* | Total formula weight | 138841.8 |