5Y44
A novel moderator XD4 for bile acid receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bile acid receptor | polymer | 227 | 26553.5 | 1 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
| 2 | B (B) | Peptide from Nuclear receptor coactivator 1 | polymer | 11 | 1430.7 | 1 | UniProt (Q15788) | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | C (A) | [(1R,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl] 4-azanyl-3-methyl-benzoate | non-polymer | 287.4 | 1 | Chemie (XD4) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A: 248 - 474 (UniProt: Q96RI1)
B: 745 - 755 (UniProt: Q15788)
| PDB | External Database | Details |
|---|---|---|
| Ala 281 | Glu 281 | conflict |
| Lys 436 | Cys 436 | conflict |
| - | Asn 461 | deletion |
| Gln 469 | Cys 470 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 745 | Asp 745 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27984.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 383.5 | |
| All* | Total formula weight | 28367.7 |
