5Y3S
Crystal structure of human NLRP1 leucine rich repeat domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NACHT, LRR and PYD domains-containing protein 1 | polymer | 205 | 22790.4 | 4 | UniProt (Q9C000) Pfam (PF00560) Pfam (PF13516) | Homo sapiens (Human) | Caspase recruitment domain-containing protein 7,Death effector filament-forming ced-4-like apoptosis protein,Nucleotide-binding domain and caspase recruitment domain |
| 2 | E, G (A, C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 790 - 990 (UniProt: Q9C000)
| PDB | External Database | Details |
|---|---|---|
| Gly 786 | - | expression tag |
| Ser 787 | - | expression tag |
| Val 788 | - | expression tag |
| Asp 789 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91161.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 212.9 | |
| All* | Total formula weight | 91374.5 |
