5Y3R
Cryo-EM structure of Human DNA-PK Holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | X-ray repair cross-complementing protein 6 | polymer | 501 | 57619.4 | 1 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (Human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 2 | B | X-ray repair cross-complementing protein 5 | polymer | 536 | 60973.0 | 1 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (Human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | K | PRKDC-Helix | polymer | 15 | 1084.2 | 1 | Homo sapiens | ||
| 4 | D | DNA (34-MER) | polymer | 34 | 10502.8 | 1 | Homo sapiens | ||
| 5 | E | DNA (36-MER) | polymer | 36 | 11042.2 | 1 | Homo sapiens | ||
| 6 | C | DNA-dependent protein kinase catalytic subunit | polymer | 4119 | 468885.3 | 1 | UniProt (P78527) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) In PDB | Homo sapiens (Human) | DNA-PKcs,DNPK1,p460 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 610106.8 | |
| All* | Total formula weight | 610106.8 |
