5Y3Q

Crystal structure of SARS coronavirus papain-like protease conjugated with beta-mercaptoethanol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Replicase polyprotein 1a	polymer	323	36462.2	1	UniProt (P0C6U8) Pfam (PF08715) In PDB	Human SARS coronavirus (SARS-CoV)	pp1a,ORF1a polyprotein
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A	BETA-MERCAPTOETHANOL	non-polymer		78.1	1	Chemie (BME)
4	A	SODIUM ION	non-polymer		23.0	5	Chemie (NA)
5	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6		water	water		18.0	294	Chemie (HOH)

Sequence modifications

A: 2 - 315 (UniProt: P0C6U8)

PDB	External Database	Details
Met 1	-	initiating methionine
Leu 316	-	expression tag
Glu 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36462.2
Non-Polymers*	Number of molecules	9
	Total formula weight	442.7
All*	Total formula weight	36904.9

*Water molecules are not included.