5Y32

Crystal structure of PTP delta Ig1-Ig2 in complex with IL1RAPL1

Replaces:  4YFC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Interleukin-1 receptor accessory protein-like 1	polymer	346	39617.1	1	UniProt (P59823) Pfam (PF18452) Pfam (PF00047)	Mus musculus (Mouse)	IL1RAPL-1,X-linked interleukin-1 receptor accessory protein-like 1
2	B (A)	Receptor-type tyrosine-protein phosphatase delta	polymer	305	33688.0	1	UniProt (Q64487) Pfam (PF07679) Pfam (PF13927)	Mus musculus (Mouse)	R-PTP-delta
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
4	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	E (E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	F, G (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	H, I (B, A)	water	water		18.0	77	Chemie (HOH)

Sequence modifications

B: 19 - 352 (UniProt: P59823)

PDB	External Database	Details
Pro 14	-	expression tag
Ala 15	-	expression tag
Ala 16	-	expression tag
Arg 17	-	expression tag
Asp 18	-	expression tag
Lys 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag
His 358	-	expression tag
His 359	-	expression tag

A: 28 - 325 (UniProt: Q64487)

PDB	External Database	Details
Lys 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73305.1
Branched	Number of molecules	3
	Total formula weight	1727.6
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	75475.1

*Water molecules are not included.