5Y2O
Structure of PPARgamma ligand binding domain-pioglitazone complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 294 | 33376.6 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | A | (5S)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione | non-polymer | 356.4 | 1 | Chemie (8N6) | |||
3 | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A, B: 207 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Met 184 | - | expression tag |
Gly 185 | - | expression tag |
Ser 186 | - | expression tag |
Ser 187 | - | expression tag |
His 188 | - | expression tag |
His 189 | - | expression tag |
His 190 | - | expression tag |
His 191 | - | expression tag |
His 192 | - | expression tag |
His 193 | - | expression tag |
Ser 194 | - | expression tag |
Ser 195 | - | expression tag |
Gly 196 | - | expression tag |
Leu 197 | - | expression tag |
Val 198 | - | expression tag |
Pro 199 | - | expression tag |
Arg 200 | - | expression tag |
Gly 201 | - | expression tag |
Ser 202 | - | expression tag |
Ala 203 | - | expression tag |
Met 204 | - | expression tag |
Gly 205 | - | expression tag |
Ser 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66753.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 356.4 | |
All* | Total formula weight | 67109.7 |