5Y1Q
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M1 family aminopeptidase | polymer | 914 | 106291.5 | 1 | UniProt (O96935) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) | Plasmodium falciparum | Pfa-M1 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | F (A) | (2S)-2-[(3-chlorophenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide | non-polymer | 313.8 | 1 | Chemie (8L0) | |||
| 5 | G (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 195 - 1085 (UniProt: O96935)
| PDB | External Database | Details |
|---|---|---|
| Met 172 | - | expression tag |
| Gly 173 | - | expression tag |
| Ser 174 | - | expression tag |
| Ser 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
| His 178 | - | expression tag |
| His 179 | - | expression tag |
| His 180 | - | expression tag |
| His 181 | - | expression tag |
| Ser 182 | - | expression tag |
| Ser 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Leu 185 | - | expression tag |
| Val 186 | - | expression tag |
| Pro 187 | - | expression tag |
| Arg 188 | - | expression tag |
| Gly 189 | - | expression tag |
| Ser 190 | - | expression tag |
| His 191 | - | expression tag |
| Met 192 | - | expression tag |
| Ala 193 | - | expression tag |
| Ser 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 106291.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 452.1 | |
| All* | Total formula weight | 106743.6 |
