5Y1B
Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with a berberine derivative (SYSU-00679)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-hexosaminidase | polymer | 578 | 66380.8 | 1 | UniProt (Q06GJ0) Pfam (PF14845) Pfam (PF00728) | Ostrinia furnacalis (Asian corn borer) | |
| 2 | B, C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D (A) | 9-O-3'-quinolinium propylberberine | non-polymer | 492.6 | 1 | Chemie (8KL) | |||
| 4 | E (A) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence modifications
A: 23 - 594 (UniProt: Q06GJ0)
| PDB | External Database | Details |
|---|---|---|
| Leu 243 | Phe 243 | engineered mutation |
| Phe 570 | Leu 570 | engineered mutation |
| His 595 | - | expression tag |
| His 596 | - | expression tag |
| His 597 | - | expression tag |
| His 598 | - | expression tag |
| His 599 | - | expression tag |
| His 600 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66380.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 935.0 | |
| All* | Total formula weight | 67315.8 |
