5XXD
Crystal structure of SmyD3 in complex with covalent inhibitor 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Smyd3 methyltransferase | polymer | 423 | 48602.5 | 1 | Pfam (PF00856) Pfam (PF01753) UniProt (by SIFTS) (Q9H7B4) | Homo sapiens | |
| 2 | B (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 3 | C, D, E (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F (A) | ethyl 4-(5,6,7,8-tetrahydroacridin-3-ylcarbonyl)piperazine-1-carboxylate | non-polymer | 367.4 | 1 | Chemie (8NR) | |||
| 5 | G (A) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48602.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 962.1 | |
| All* | Total formula weight | 49564.6 |
