5XW6
Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, A, B | P2X purinoceptor | polymer | 327 | 37341.8 | 3 | UniProt (E1C6P3) In PDB | Gallus gallus (Chicken) | |
2 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
3 | C, A, B | SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE | non-polymer | 718.3 | 3 | Chemie (128) |
Sequence modifications
C, A, B: 28 - 346 (UniProt: E1C6P3)
PDB | External Database | Details |
---|---|---|
Gly 22 | - | expression tag |
Ser 23 | - | expression tag |
Gly 24 | - | expression tag |
Ser 25 | - | expression tag |
Gly 26 | - | expression tag |
Ser 27 | - | expression tag |
Gln 190 | Asn 204 | engineered mutation |
Leu 347 | - | expression tag |
Glu 348 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 112025.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2818.4 | |
All* | Total formula weight | 114844.0 |