5XW6
Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (C, A, B) | P2X purinoceptor | polymer | 327 | 37341.8 | 3 | UniProt (E1C6P3) | Gallus gallus (Chicken) | |
| 2 | D, G, I (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E, F, H (C, A, B) | SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE | non-polymer | 718.3 | 3 | Chemie (128) |
Sequence modifications
C, A, B: 28 - 346 (UniProt: E1C6P3)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Gln 190 | Asn 204 | engineered mutation |
| Leu 347 | - | expression tag |
| Glu 348 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112025.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2818.4 | |
| All* | Total formula weight | 114844.0 |
