5XVF
Crystal Structure of PAK4 in complex with inhibitor CZH062
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PAK 4 | polymer | 290 | 32683.0 | 1 | UniProt (O96013) Pfam (PF00069) In PDB | Homo sapiens (Human) | p21-activated kinase 4,PAK-4 |
| 2 | A | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine | non-polymer | 357.8 | 1 | Chemie (8FR) | |||
| 3 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 300 - 588 (UniProt: O96013)
| PDB | External Database | Details |
|---|---|---|
| Ser 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32683.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 357.8 | |
| All* | Total formula weight | 33040.8 |
