5XSM

Crystal Structure of Transketolase in complex with TPP intermediate IV from Pichia Stipitis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transketolase	polymer	697	75054.5	1	UniProt (P34736) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780) In PDB	Scheffersomyces stipitis CBS 6054 (Yeast)	TK
2	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
3	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
4	A	2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2,5-dihydro-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate	non-polymer		427.3	1	Chemie (8EO)
5		water	water		18.0	800	Chemie (HOH)

Sequence modifications

A: 1 - 677 (UniProt: P34736)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	75054.5
Non-Polymers*	Number of molecules	5
	Total formula weight	785.8
All*	Total formula weight	75840.2

*Water molecules are not included.