5XOT
Crystal structure of pHLA-B35 in complex with TU55 T cell receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, B-35 alpha chain | polymer | 276 | 31956.2 | 1 | UniProt (P30685) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (Human) | MHC class I antigen B*35 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | An HIV reverse transcriptase epitope | polymer | 9 | 1014.1 | 1 | UniProt (by SIFTS) (P04585) | Human immunodeficiency virus 1 | |
| 4 | D (D) | The Delta chain of TU55 TCR | polymer | 204 | 22844.7 | 1 | Homo sapiens | ||
| 5 | E (E) | The beta chain of TU55 TCR | polymer | 242 | 27342.5 | 1 | Homo sapiens | ||
| 6 | F, G, H (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | I, J, K, L (A, B, D, E) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P30685)
| PDB | External Database | Details |
|---|---|---|
| Asp 34 | Val 58 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 94905.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 95181.9 |
