5XOC
Crystal structure of human Smad3-FoxH1 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mothers against decapentaplegic homolog 3 | polymer | 199 | 22463.5 | 1 | UniProt (P84022) Pfam (PF03166) In PDB | Homo sapiens (Human) | hMAD-3,JV15-2,SMAD family member 3,hSMAD3 |
2 | B | Thioredoxin 1,Forkhead box protein H1 | polymer | 141 | 15437.6 | 1 | UniProt (P0AA25) UniProt (O75593) Pfam (PF00085) In PDB | Escherichia coli (strain K12) | Trx-1,Forkhead activin signal transducer 1,hFAST-1,Forkhead activin signal transducer 2,Fast-2 |
3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 220 - 416 (UniProt: P84022)
B: 212 - 319 (UniProt: P0AA25)
B: 322 - 345 (UniProt: O75593)
PDB | External Database | Details |
---|---|---|
Gly 218 | - | expression tag |
Pro 219 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 205 | - | initiating methionine |
His 206 | - | expression tag |
His 207 | - | expression tag |
His 208 | - | expression tag |
His 209 | - | expression tag |
His 210 | - | expression tag |
His 211 | - | expression tag |
Gly 320 | - | linker |
Ser 321 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37901.1 | |
All* | Total formula weight | 37901.1 |