5XMS

Plasmodium vivax SHMT bound with PLP-glycine and GS498

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Serine hydroxymethyltransferase	polymer	442	49249.2	3	UniProt (A0A1G4H5I1) Pfam (PF00464) UniProt (by SIFTS) (A5K8L9)	Plasmodium vivax
2	D, G, I (A, B, C)	N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]	non-polymer		306.2	3	Chemie (PLG)
3	E, H, J (A, B, C)	(4~{S})-6-azanyl-4-[3-(2-fluorophenyl)-5-(trifluoromethyl)phenyl]-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazole-5- carbonitrile	non-polymer		456.4	3	Chemie (8B3)
4	F, K (A, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	L, M, N (A, B, C)	water	water		18.0	330	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	147747.5
Non-Polymers*	Number of molecules	8
	Total formula weight	2358.8
All*	Total formula weight	150106.3

*Water molecules are not included.