5XMQ
Plasmodium vivax SHMT(C346A) bound with PLP-glycine and MF011
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine hydroxymethyltransferase | polymer | 442 | 49217.1 | 3 | UniProt (A0A1G4H5I1) Pfam (PF00464) UniProt (by SIFTS) (A5K8L9) | Plasmodium vivax | |
| 2 | D, G, I (A, B, C) | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | non-polymer | 306.2 | 3 | Chemie (PLG) | |||
| 3 | E, H, J (A, B, C) | 4-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]-~{N}-methyl-~{N}-(phenylmethyl)benzenesulfonamide | non-polymer | 621.7 | 3 | Chemie (8A6) | |||
| 4 | F, K (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | L, M, N (A, B, C) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 442 (UniProt: A0A1G4H5I1)
| PDB | External Database | Details |
|---|---|---|
| Ala 364 | Cys 364 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 147651.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2854.6 | |
| All* | Total formula weight | 150505.8 |
