5XJY
Cryo-EM structure of human ABCA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette sub-family A member 1 | polymer | 2305 | 259513.0 | 1 | UniProt (O95477) Pfam (PF12698) Pfam (PF00005) | Homo sapiens (Human) | ATP-binding cassette transporter 1,ATP-binding cassette 1,Cholesterol efflux regulatory protein |
| 2 | B (B) | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G89225LT) | |||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, F, G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A: 1 - 2261 (UniProt: O95477)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Ala -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Lys -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Pro -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Leu 2262 | - | expression tag |
| Glu 2263 | - | expression tag |
| Gly 2264 | - | expression tag |
| Ser 2265 | - | expression tag |
| Asp 2266 | - | expression tag |
| Glu 2267 | - | expression tag |
| Val 2268 | - | expression tag |
| Asp 2269 | - | expression tag |
| Ala 2270 | - | expression tag |
| Val 2271 | - | expression tag |
| Glu 2272 | - | expression tag |
| Gly 2273 | - | expression tag |
| Ser 2274 | - | expression tag |
| His 2275 | - | expression tag |
| His 2276 | - | expression tag |
| His 2277 | - | expression tag |
| His 2278 | - | expression tag |
| His 2279 | - | expression tag |
| His 2280 | - | expression tag |
| His 2281 | - | expression tag |
| His 2282 | - | expression tag |
| His 2283 | - | expression tag |
| His 2284 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 259513.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 261954.2 |
