5XJA

The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-AlFx

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Kinesin-like protein KIF2C	polymer	426	48453.5	2	UniProt (Q922S8) Pfam (PF00225) In PDB	Mus musculus (Mouse)	Mitotic centromere-associated kinesin,MCAK
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	A, B	ALUMINUM FLUORIDE	non-polymer		84.0	2	Chemie (AF3)
5		water	water		18.0	7	Chemie (HOH)

Sequence modifications

A, B: 183 - 585 (UniProt: Q922S8)

PDB	External Database	Details
Met 167	-	initiating methionine
Ala 168	-	expression tag
Ser 169	-	expression tag
Met 170	-	expression tag
Thr 171	-	expression tag
Gly 172	-	expression tag
Gly 173	-	expression tag
Gln 174	-	expression tag
Gln 175	-	expression tag
Met 176	-	expression tag
Gly 177	-	expression tag
Arg 178	-	expression tag
Asp 179	-	expression tag
Pro 180	-	expression tag
Asn 181	-	expression tag
Ser 182	-	expression tag
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96907.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1071.0
All*	Total formula weight	97978.1

*Water molecules are not included.