5XG4
Crystal structure of uPA in complex with quercetin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | U | Urokinase-type plasminogen activator | polymer | 246 | 27715.6 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (Human) | uPA |
| 2 | U | 3,5,7,3',4'-PENTAHYDROXYFLAVONE | non-polymer | 302.2 | 1 | Chemie (QUE) | |||
| 3 | U | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | non-polymer | 266.3 | 1 | Chemie (PG6) | |||
| 4 | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
U: 16 - 243 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | conflict |
| Gln 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27715.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 568.6 | |
| All* | Total formula weight | 28284.2 |
