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5XEJ

Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX

Replaces:  5CG4
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Macrophage migration inhibitory factorpolymer11412355.13UniProt (P14174)
Pfam (PF01187)
Homo sapiens (Human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2D, E, F, H
(A, C)
SULFATE IONnon-polymer96.14Chemie (SO4)
3G
(A)
(2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acidnon-polymer454.41Chemie (6UV)
4I, J, K
(A, B, C)
waterwater18.048Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37065.2
Non-Polymers*Number of molecules5
Total formula weight838.7
All*Total formula weight37903.9
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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