5X8D
D90L mutant of thermus thermophilus HB8 thymidylate kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Thymidylate kinase | polymer | 198 | 22007.6 | 2 | UniProt (Q5SHX3) Pfam (PF02223) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | dTMP kinase |
| 2 | C, D, G, H (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, F, I (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 4 | J, K (B, A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 198 (UniProt: Q5SHX3)
| PDB | External Database | Details |
|---|---|---|
| Leu 90 | Asp 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44015.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 415.6 | |
| All* | Total formula weight | 44430.8 |
