5X6R

Crystal structure of Saccharomyces cerevisiae KMO in complex with Ro 61-8048

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kynurenine 3-monooxygenase	polymer	420	47913.6	2	UniProt (P38169) Pfam (PF01494)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Biosynthesis of nicotinic acid protein 4,Kynurenine 3-hydroxylase
2	C, E (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	D, F (A, B)	3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide	non-polymer		421.4	2	Chemie (7ZR)
4	G, H (A, B)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

A, B: 1 - 394 (UniProt: P38169)

PDB	External Database	Details
Met -25	-	expression tag
Arg -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Asp -15	-	expression tag
Tyr -14	-	expression tag
Asp -13	-	expression tag
Ile -12	-	expression tag
Pro -11	-	expression tag
Thr -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95827.2
Non-Polymers*	Number of molecules	4
	Total formula weight	2414.0
All*	Total formula weight	98241.2

*Water molecules are not included.