5X5U

Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (KGSADH) complexed with NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alpha-ketoglutaric semialdehyde dehydrogenase	polymer	505	53857.1	2	UniProt (Q1JUP4) Pfam (PF00171)	Azospirillum brasilense	alphaKGSA dehydrogenase,2,5-dioxovalerate dehydrogenase,2-oxoglutarate semialdehyde dehydrogenase,Succinate-semialdehyde dehydrogenase [NAD(+)],SSDH
2	C, E (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F, G (A, B)	water	water		18.0	558	Chemie (HOH)

Sequence modifications

A, B: 2 - 481 (UniProt: Q1JUP4)

PDB	External Database	Details
Met -23	-	expression tag
Ser -22	-	expression tag
Tyr -21	-	expression tag
Tyr -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Asp -13	-	expression tag
Tyr -12	-	expression tag
Asp -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Thr -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Ile -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Ala 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	107714.2
Non-Polymers*	Number of molecules	3
	Total formula weight	1418.9
All*	Total formula weight	109133.1

*Water molecules are not included.