5X5O
Crystal structure of ZAK in complex with compound D2829
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase kinase kinase MLT | polymer | 310 | 35337.5 | 1 | UniProt (Q9NYL2) Pfam (PF07714) | Homo sapiens (Human) | Human cervical cancer suppressor gene 4 protein,HCCS-4,Leucine zipper- and sterile alpha motif-containing kinase,MLK-like mitogen-activated protein triple kinase,Mixed lineage kinase-related kinase,MRK,Sterile alpha motif- and leucine zipper-containing kinase AZK |
| 2 | B (A) | N-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide | non-polymer | 519.3 | 1 | Chemie (7Z0) | |||
| 3 | C (A) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 5 - 309 (UniProt: Q9NYL2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Met 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35337.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 519.3 | |
| All* | Total formula weight | 35856.8 |
