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5X5D

Human thymidylate synthase bound with dUMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Thymidylate synthasepolymer29033254.16UniProt (P04818)
Pfam (PF00303)
Homo sapiens (Human)TSase
2G, H, I, J, K...
(A, B, C, D, E...)
2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.26Chemie (UMP)
3M, N, O, P, Q...
(A, B, C, D, E...)
waterwater18.01624Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 26 - 313 (UniProt: P04818)
PDBExternal DatabaseDetails
Ser 24-expression tag
Met 25-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight199524.8
Non-Polymers*Number of molecules6
Total formula weight1849.1
All*Total formula weight201373.8
*Water molecules are not included.

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PDB entries from 2025-12-10

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