5X5C

Prefusion structure of MERS-CoV spike glycoprotein, conformation 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	S protein	polymer	1323	145856.2	3	UniProt (W6A028) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (K9N5Q8)	Middle East respiratory syndrome coronavirus	Spike glycoprotein,Spike protein

Sequence modifications

A, B, C: 18 - 1294 (UniProt: W6A028)

PDB	External Database	Details
Ser 751	Arg 751	engineered mutation
Gln 1020	Arg 1020	engineered mutation
Glu 1295	-	expression tag
Phe 1296	-	expression tag
Arg 1297	-	expression tag
Leu 1298	-	expression tag
Val 1299	-	expression tag
Pro 1300	-	expression tag
Arg 1301	-	expression tag
Gly 1302	-	expression tag
Ser 1303	-	expression tag
Pro 1304	-	expression tag
Gly 1305	-	expression tag
Ser 1306	-	expression tag
Gly 1307	-	expression tag
Tyr 1308	-	expression tag
Ile 1309	-	expression tag
Pro 1310	-	expression tag
Glu 1311	-	expression tag
Ala 1312	-	expression tag
Pro 1313	-	expression tag
Arg 1314	-	expression tag
Asp 1315	-	expression tag
Gly 1316	-	expression tag
Gln 1317	-	expression tag
Ala 1318	-	expression tag
Tyr 1319	-	expression tag
Val 1320	-	expression tag
Arg 1321	-	expression tag
Lys 1322	-	expression tag
Asp 1323	-	expression tag
Gly 1324	-	expression tag
Glu 1325	-	expression tag
Trp 1326	-	expression tag
Val 1327	-	expression tag
Leu 1328	-	expression tag
Leu 1329	-	expression tag
Ser 1330	-	expression tag
Thr 1331	-	expression tag
Phe 1332	-	expression tag
Leu 1333	-	expression tag
Gly 1334	-	expression tag
His 1335	-	expression tag
His 1336	-	expression tag
His 1337	-	expression tag
His 1338	-	expression tag
His 1339	-	expression tag
His 1340	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	437568.6
All*	Total formula weight	437568.6

*Water molecules are not included.