5X4X
Mutant human thymidylate synthase A191K crystallized in a sulfate-containing condition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase | polymer | 314 | 35908.1 | 1 | UniProt (P04818) Pfam (PF00303) | Homo sapiens (Human) | TSase |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 313 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Lys 191 | Ala 191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35908.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 36100.2 |
