5X2P
Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with L-glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Taste receptor, type 1, member 2a | polymer | 461 | 51471.1 | 2 | UniProt (A0A173M0G2) Pfam (PF01094) In PDB | Oryzias latipes (Japanese rice fish) | T1r2a |
| 2 | B, D | Taste receptor, type 1, member 3 | polymer | 478 | 53132.0 | 2 | UniProt (A0A173M094) Pfam (PF01094) In PDB | Oryzias latipes (Japanese rice fish) | T1r3 |
| 3 | H, J | Fab16A Heavy chain | polymer | 225 | 24182.2 | 2 | Mus musculus (Mouse) | ||
| 4 | L, K | Fab16A Light chain | polymer | 217 | 23899.2 | 2 | Mus musculus (Mouse) | ||
| 5 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | C, A, D, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 23 | Chemie (NAG) | |||
| 8 | C, D, A, B | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 9 | C, A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 10 | B, D | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 11 | K | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 12 | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A, C: 20 - 474 (UniProt: A0A173M0G2)
B, D: 20 - 491 (UniProt: A0A173M094)
| PDB | External Database | Details |
|---|---|---|
| Ser 475 | - | expression tag |
| Gly 476 | - | expression tag |
| Ile 477 | - | expression tag |
| Glu 478 | - | expression tag |
| Gly 479 | - | expression tag |
| Arg 480 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 492 | - | expression tag |
| Gly 493 | - | expression tag |
| Ile 494 | - | expression tag |
| Glu 495 | - | expression tag |
| Gly 496 | - | expression tag |
| Arg 497 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 305369.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 5833.3 | |
| All* | Total formula weight | 312213.3 |
