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5X03

Crystal structure of the C-terminal domain of Bacillus subtilis GabR reveals a closed conformation by the binding of gamma-aminobutyric acid, inducing the transcriptional activation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HTH-type transcriptional regulatory protein GabRpolymer36341820.01UniProt (P94426)
Pfam (PF00155)
Bacillus subtilis (strain 168)
2B
(B)
HTH-type transcriptional regulatory protein GabRpolymer36542115.31UniProt (P94426)
Pfam (PF00155)
Bacillus subtilis (strain 168)
3C, E
(A, B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.12Chemie (PLP)
4D
(A)
GAMMA-AMINO-BUTANOIC ACIDnon-polymer103.11Chemie (ABU)
5F, G
(A, B)
waterwater18.0248Chemie (HOH)
Sequence modifications
B: 108 - 472 (UniProt: P94426)
PDBExternal DatabaseDetails
Arg 472Lys 472engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight83935.3
Non-Polymers*Number of molecules3
Total formula weight597.4
All*Total formula weight84532.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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