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5WZW

Crystal structure of human secreted phospholipase A2 group IIE with LY311727

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Group IIE secretory phospholipase A2polymer12313986.11UniProt (Q9NZK7)
Pfam (PF00068)
Homo sapiens (Human)sPLA2-IIE,Phosphatidylcholine 2-acylhydrolase 2E
2B, C, D, E, F...
(A)
CHLORIDE IONnon-polymer35.57Chemie (CL)
3I
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4J
(A)
(3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acidnon-polymer430.41Chemie (U8D)
5K, L
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
6M
(A)
waterwater18.0163Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13986.1
Non-Polymers*Number of molecules11
Total formula weight902.9
All*Total formula weight14889.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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