5WWX

Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-binding E3 ubiquitin-protein ligase MEX3C	polymer	86	9772.2	1	UniProt (Q5U5Q3) Pfam (PF00013) In PDB	Homo sapiens (Human)	RING finger and KH domain-containing protein 2,RING finger protein 194,RING-type E3 ubiquitin transferase MEX3C
2	C	RNA (5'-R(P*AP*GP*AP*GP*U)-3')	polymer	5	1610.0	1		synthetic construct
3	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
4		water	water		18.0	62	Chemie (HOH)

Sequence modifications

A: 320 - 396 (UniProt: Q5U5Q3)

PDB	External Database	Details
Met 311	-	expression tag
Gly 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
Met 319	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	11382.3
Non-Polymers*	Number of molecules	1
	Total formula weight	58.7
All*	Total formula weight	11440.9

*Water molecules are not included.