5WVC

Structure of the CARD-CARD disk

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (C, A, E)	Apoptotic protease-activating factor 1	polymer	95	10925.6	3	UniProt (O14727) Pfam (PF00619)	Homo sapiens (Human)	APAF-1
2	B, D, F (D, B, F)	Caspase	polymer	151	17410.0	3	UniProt (A8K7U6) Pfam (PF00619) UniProt (by SIFTS) (P55211)	Homo sapiens (Human)
3	G, H, I, J, K... (C, D, B, E, F)	IODIDE ION	non-polymer		126.9	11	Chemie (IOD)

Sequence modifications

D, B, F: 201 - 328 (UniProt: A8K7U6)

PDB	External Database	Details
Met 178	-	expression tag
Gly 179	-	expression tag
Ser 180	-	expression tag
Ser 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
Ser 188	-	expression tag
Ser 189	-	expression tag
Gly 190	-	expression tag
Leu 191	-	expression tag
Val 192	-	expression tag
Pro 193	-	expression tag
Arg 194	-	expression tag
Gly 195	-	expression tag
Ser 196	-	expression tag
His 197	-	expression tag
Met 198	-	expression tag
Ala 199	-	expression tag
Ser 200	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	85006.6
Non-Polymers*	Number of molecules	11
	Total formula weight	1395.9
All*	Total formula weight	86402.6

*Water molecules are not included.