5WT9
Complex structure of PD-1 and nivolumab-Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Heavy Chain of Nivolumab | polymer | 220 | 23679.5 | 1 | Homo sapiens (Human) | ||
| 2 | B (L) | Light Chain of Nivolumab | polymer | 217 | 23641.1 | 1 | Homo sapiens (Human) | ||
| 3 | C (G) | Programmed cell death protein 1 | polymer | 173 | 19646.0 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 5 | E, F, G (H, L, G) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
G: 1 - 167 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66966.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 67537.3 |
