5WRK

Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	AP-2 complex subunit mu	polymer	278	30911.7	1	UniProt (P84092) Pfam (PF00928)	Rattus norvegicus (Rat)	AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein
2	B (P)	Insulin receptor substrate 1	polymer	8	839.0	1	UniProt (P35570)	Rattus norvegicus	IRS-1,pp185
3	C, D (A)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)

Sequence modifications

A: 158 - 223 (UniProt: P84092)
A: 224 - 260 (PDB: 5WRK)
A: 261 - 435 (UniProt: P84092)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31750.7
Non-Polymers*	Number of molecules	2
	Total formula weight	117.4
All*	Total formula weight	31868.1

*Water molecules are not included.