5WN1
APE1 exonuclease product complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 276 | 31156.5 | 2 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (Human) | APEX1, APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1, APE-1, REF-1, Redox factor-1 |
| 2 | C (C) | DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3') | polymer | 11 | 3334.2 | 1 | synthetic construct | ||
| 3 | D (D) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*G)-3') | polymer | 9 | 2771.8 | 1 | synthetic construct | ||
| 4 | E (E) | DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 21 | 6424.1 | 1 | synthetic construct | ||
| 5 | F (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G, I (B, E) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H (E) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | J, K, L, M, N (A, B, C, D, E) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Ala 138 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 74843.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 121.5 | |
| All* | Total formula weight | 74964.6 |
