5WMT
Structure of GRP94 N-terminal Domain bound to resorcinylic inhibitor BnIm.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Endoplasmin | polymer | 236 | 26514.0 | 4 | UniProt (P41148) Pfam (PF13589) | Canis lupus familiaris (Dog) | 94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1,94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1 |
| 2 | E, F, G, H, J... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 3 | I, N, T, Y (A, B, C, D) | methyl 2-[2-(1-benzyl-1H-imidazol-2-yl)ethyl]-3-chloro-4,6-dihydroxybenzoate | non-polymer | 386.8 | 4 | Chemie (9QY) | |||
| 4 | M, S (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 69 - 286 (UniProt: P41148)
A, B, C, D: 328 - 337 (UniProt: P41148)
| PDB | External Database | Details |
|---|---|---|
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| His 67 | - | expression tag |
| Met 68 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 324 | - | linker |
| Gly 325 | - | linker |
| Gly 326 | - | linker |
| Gly 327 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106056.0 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2526.9 | |
| All* | Total formula weight | 108583.0 |
