5WMT

Structure of GRP94 N-terminal Domain bound to resorcinylic inhibitor BnIm.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Endoplasmin	polymer	236	26514.0	4	UniProt (P41148) Pfam (PF13589) In PDB	Canis lupus familiaris (Dog)	94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1,94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1
2	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	15	Chemie (EDO)
3	A, B, C, D	methyl 2-[2-(1-benzyl-1H-imidazol-2-yl)ethyl]-3-chloro-4,6-dihydroxybenzoate	non-polymer		386.8	4	Chemie (9QY)
4	B, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5		water	water		18.0	60	Chemie (HOH)

Sequence modifications

A, B, C, D: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	expression tag
Ser 66	-	expression tag
His 67	-	expression tag
Met 68	-	expression tag

A, B, C, D: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 324	-	linker
Gly 325	-	linker
Gly 326	-	linker
Gly 327	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	106056.0
Non-Polymers*	Number of molecules	21
	Total formula weight	2526.9
All*	Total formula weight	108583.0

*Water molecules are not included.